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however, this balance can often be disrupted by biotic or abiotic stressors such as superoxide radicals, endogenous lipids, DNA hydroperoxides, hydrogen peroxide, hydroxyl radicals, and hydroxy alkenals

Behavioral assessments, including rotarod, cylinder, adhesive, and grid-walking tests (Fig

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This exceptional BBB permeability stems from its relatively small molecular weight of 750 Da and specific structural modifications that allow passive diffusion across endothelial tight junctions

DSIP has been studied for potential interaction with hypothalamic nuclei involved in sleep-wake control and stress integration