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However, in a large study involving people with diabetes who had no comorbidities, GLP-1 RAs were not shown to increase the risk of developing pancreatitis at any time point up through 5 years of use.[ref][ref][ref][ref] The Cleveland Clinic now counsels that GLP-1 RA patients should be screened for pancreatitis risk factors, and a lower dose should be used to reduce the risk of pancreatitis.[ref] Related article : Pancreatitis and Genetic Risk Factors Gastroparesis: Case reports tie semaglutide to a risk of gastroparesis (very slow stomach emptying)

GLP-1 also helps manage blood sugar by slowing how fast the stomach empties food and boosting insulin release after meals

However, like many medications, semaglutide has side effects

This step is based on how well the patient is doing with the medication

Frequently asked questions about medical expenses related to nutrition, wellness and general health