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Sci Rep 13(1):4231

doi: 10.1016/j.molmet.2021.101181 [DOI] [PMC free article] [PubMed] [Google Scholar] 64.Widmann C, Dolci W, Thorens B

Layering an extremely restrictive diet on top of that can backfire by triggering excessive muscle loss, nutrient deficiencies, fatigue, and metabolic adaptation

Heres who I think its best for: Women in menopause struggling with weight gain who want an affordable GLP-1 option

These include: Nausea (affecting 20-40% of patients initially) Vomiting Diarrhoea Constipation Abdominal discomfort These symptoms can be debilitating during the first few weeks of treatment and may cause fatigue, reduced appetite, and general malaise