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The crosstalk between inflammation and ferroptosis has been systematically reviewed, however, its specific role in the CNS, especially in depression, has not been thoroughly addressed

Inflammation and gut microbiota play crucial roles in both psychological distress and liver disease initiation and progression, while the sickness behavior theory explains that peripheral inflammation can lead to behaviors like fatigue, lethargy, impaired concentration, and social withdrawal

2) div-1(RNAi) from L4 staged larvae partially enhanced a Glp phenotype in adult glp-1(bn18) mutant germlines (Fig

It could limit and prevent the overproduction of ROS (160) and suppress the activation of the NLRP3 inflammasome in the renal tubules (155)