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In the co-culture system, MCECs derived from the model group exhibited significant reduced ZO-1 and Occludin expression compared to those from the Control group, whereas GHK-Cu elevated theses protein levels (Figures 4GI)

Trepanowski JF, Mey J, Varady KA

As a Class B G-protein-coupled receptor (GPCR), GLP-1R regulates tumorigenesis through multiple signaling pathways

Kirsch, M

The former reflects a proportional decrease in lean tissue during negative energy balance and is typically expected to account for roughly one-quarter of the total weight loss, whereas the latter involves both quantitative loss of skeletal muscle and impaired muscle function or strength [19]