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After the nervous system is damaged, the dysfunction of the nervous system can also continue to cause oxidative stress in different ways, which is an everamplifying vicious cycle process

After cleavage by LAL, free cholesterol and fatty acids exit the lysosome to enter the cytosol (Figure 1)

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Thus, GLP-1 receptor agonists like semaglutide may be beneficial for islet structural remodeling and their endocrine function in diet-induced obese mice and associated with food intake

Study follow-up and measurements Study follow-up and measurements After the baseline visit, the patients were followed up every 3 months