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The American Association of Clinical Endocrinology (AACE) 2023 consensus statement reclassified obesity as a chronic, relapsing disease requiring long-term pharmacotherapy

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Wherein: i) the compound of Formula E used in step c) is prepared by a process comprising the reaction of a compound of Formula Ei Formula E1 with a carboxylic acid activator and, ii) the compound of Formula G used in step e) is prepared by a process comprising the steps of: fl) coupling a compound of Formula H 2