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The better question is which side effect profile is more manageable for you

This ensures each injection site heals properly while you maintain convenient thigh injections

Study author Sun H Kim, MD, MS, Associate Professor of Medicine in the Division of Endocrinology, Gerontology, and Metabolism at Stanford, summarized the findings to to Medical News Today , saying: We found that semaglutide compared to other weight loss medications, including another GLP-1 medication called dulaglutide, reduced risk of future fractures despite being associated with greater weight loss. Overall, semaglutide was linked to a bigger decrease in BMI

Heres a four-week example you can copy to your calendar and repeat: Week 1 (Sun): Abdomen left upper-outer square Week 2 (Sun): Right thigh middle third, upper half Week 3 (Sun): Left upper arm outer back, upper half Week 4 (Sun): Abdomen right lower-outer square Then continue the sequence, moving to a new square within each area when it comes around again

According to clinical studies, such as the STEP clinical trials, noticeable weight loss can be observed from about four weeks onward, with more significant results becoming evident within four to five months