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Active cancer or history of malignancy Pregnancy or breastfeeding Known peptide allergies Athletes subject to anti-doping testing (WADA prohibited) Raynauds disease or phenomenon Cold urticaria (hives from cold) Uncontrolled hypertension Peripheral vascular disease Open wounds (for local application) Pregnancy Cardiovascular conditions Diabetes (especially with neuropathy) Current infections Immunosuppression Blood clotting disorders Quality control issues represent perhaps the greatest practical risk with BPC-157

45 DAY SUPPLY - 2 CAPSULES PER DAY: Each bottle contains 90 capsules for a 45-day supply

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doi: 10.1136/ard.2006.062554 150 XuMHongRZhangXZouHZhangYHouZet al

Matching accounted for demographics, body mass index (BMI), hemoglobin A1c, and multiple comorbidities