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This is the same biological mechanism that causes general dark lips after inflammation, but concentrated in a single spot rather than spread across the lip surface

BPC-157: 250 mcg subcutaneously, twice daily (morning and evening) Cryotherapy: Local ice application for 15-20 minutes every 2-3 hours during waking hours Timing: Apply cold therapy at least 30 minutes after BPC-157 injection to allow peptide absorption Rest the injured area as much as practically possible Reduce cold application frequency as acute swelling subsides

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Energy restriction has been shown to cause follicles to remain small, whereas re-establishing an adequate energy level triggers a rapid follicular growth wave in cattle (Domingues et al., 2020)