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In contrast, the expressions of PDL1, CTLA4, BTLA, TIM3, ICOS, ILDR2, and TIGIT were significantly decreased in high SLC35A39 group (Fig.7B)

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While obesity is linked to poor sperm quantity and quality and lower chance of successful pregnancy and birth, weight loss in obese men has been shown to rapidly improve sperm numbers, motility, morphology, and DNA fragmentation rate