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These programs raise particular concerns in the medical context, where patients and the larger society have a compelling need for medical education to be focused primarily on excellence and delivering the best possible care to patients

Under these circumstances, ketone bodiesespecially -hydroxybutyrate derived from FAOserve as vital alternative energy substrates (29, 30)

It is worth noting that in some cases a Direct to Phase II (D2P2) award is available, allowing a company to skip Phase I entirely and move directly into full R&D funding