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Limited Long-term Safety Data: While short-term animal studies may have demonstrated the safety of BPC-157 for human use, there is currently limited information available on systemic effects of its long-term use in humans

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Surgery Surgical options include microdiscectomy (removal of the herniated disc material), laminectomy (removal of bone to relieve pressure), and spinal fusion (permanently joining two or more vertebrae)

Enrichment of gene sets of interest were identified by Kyoto Encyclopedia of Genes and Genomes (KEGG) and REACTOME collections of MSigDB Molecular Signatures Database (MSigDB) by Gene Set Enrichment Analysis (GSEA) software (Broad Institute, USA) as described by Mootha et al

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