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Treatment with Obeticholic acid (OCA) led to the activation of the Farnesoid X receptor (FXR), inducing various oxidative stress pathways, which in turn led to the alleviation of oxidative stress induced due to VPA 16
doi: 10.1371/journal.ppat.1003581 7 AzmiS.HussainM
In the scientific community, this is often referred to as the glutathione-ascorbic acid cycle
[63] The writing staff often used their personal experiences as inspiration for storylines
Accordingly, molecules with a good affinity and selectivity for these receptors/transporters can be explored as brain-targeting agents
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