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In order to study how the metabolism of APAP affects GSH concentration and resynthesis, we have connected the model depicted in Figure1 to our extant model of glutathione metabolism[9]

doi: 10.3389/fmicb.2020.00283 Received 10 December 2019 Accepted 07 February 2020 Published 21 February 2020 Volume 11 - 2020 Edited by Fabian Cieplik, University Medical Center Regensburg, Germany Reviewed by Tianhong Dai, Harvard Medical School, United States