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Cartilage itself is not innervated, but nociceptors are present in surrounding tissues, such as the synovium and joint capsule, subchondral bone, periosteum, meniscus, and ligaments 39

The 50 mg setup is far easier to draw accurately (20 units is a clean, mid-barrel mark) because the higher concentration and larger per-dose amount land on a bigger, more forgiving volume

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The TCGA database only includes transcriptomic data for thyroid carcinomas from PTC patients, not MTC