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In the macro-vasculature, OS accelerates atherosclerosis by promoting LDL oxidation, macrophage foam cell formation, and plaque instability via matrix metalloproteinase (MMP) activation (Kowluru and Mishra, 2017), while in diabetic nephropathy, podocyte injury results from NOX4-derived O 2 and mitochondrial ROS-mediated apoptosis (Jha et al., 2024)

TUNEL method revealed a marked accumulation of DNA fragments in both the cytoplasm and nucleus of necrotic hepatocytes in the Aldh2*2 KI homozygous mice after AA exposure (Fig

Crohns Colitis 80 MenonD

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2026 SKO Compounds