Studies indicate that melatonin can preserve the integrity of tight junctions by reducing oxidative stress and suppressing the expression of pro-inflammatory cytokines (Qin et al., 2019
Zinc Contributes to healthy skin and immune balance
For example, taking very high doses of vitamin B6 can lead to potentially irreversible nerve damage over time, while taking large amounts of niacin typically in excess of 2 grams per day can cause liver damage ( Fat-soluble vitamins Unlike water-soluble vitamins, fat-soluble vitamins do not dissolve in water and are easily stored in your bodys tissues ( There are four fat-soluble vitamins: Vitamin A Vitamin D Vitamin E Vitamin K Given that fat-soluble vitamins can accumulate in the body, these nutrients are more likely to lead to toxicity than water-soluble vitamins
These factors, crucial for healthy aging, reduce the risk of age-related diseases like type 2 diabetes, heart disease, and stroke
Epigenetic clocks are well validated as research tools and have consistently been shown to predict how many healthy years people are likely to live, as well as their risk of chronic disease, disability and death
