Rational modulation of PUFA biosynthesis, including arachidonic and linoleic acids, may quell excessive inflammatory responses and concurrently optimize the metabolic environment for antioxidant defense (161)
NMN administration prevents diabetes-induced cognitive impairment by activating the SIRT1 pathway, which preserves mitochondrial function and reduces OS ( 5 Clinical application of natural antioxidants in DN 5.1 From rodent to human reality Although animal models have been extensively used in initial functional tests and mechanism research, there are also limitations that are difficult to overcome
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B., Onuki, Y., Bruinsma, B., van der Werf, Y
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