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When stimulated by HGF, MET initiates the phosphorylation of -catenin at tyrosine sites, causing its separation from MET and subsequent movement to the nucleus

The inclusion of the SLC24A5 melanin-inhibiting complex enhances whitening efficiency by directly influencing melanosome activity

[14] In severe or inherited forms of biotin deficiency (such as biotinidase deficiency), even higher daily doses may be employed, and lifelong supplementation can be necessary under medical guidance

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