There are several mechanisms for this remodeling, including cell hypertrophy, hyperplasia, and extracellular matrix remodeling (Osol and Moore, 2014)
The remainder are NP/PA-led or dont publicly name a specific prescribing clinician

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One ml throughout 45 s warmed Omnipaque 350 (iohexol) non-ionic contrast medium (GE Healthcare, Arlington Heights, IL, USA) was injected into the superior sagittal sinus anterior to ligation, into the right external jugular vein and into the inferior vena cava at the level of bifurcation of rats with a ligated superior sagittal sinus
To contextualize these percentages, a person weighing 250 pounds at baseline could expect to lose approximately 52 pounds on the 15 mg dose, 49 pounds on 10 mg, or 38 pounds on 5 mg over the study period