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This is because in the first three months of weight loss with GLP-1, supportive measures such as resistance training and sufficient protein intake can mitigate some of the sagging, hollowing and wrinkling and skin quality changes

Millions of people have a B12 deficiency

Patients requiring multifactorial risk management : Individuals with multiple cardiovascular risk factors may benefit from the pleiotropic effects of GLP-1 therapy, including blood pressure reduction, weight loss, and lipid improvements

If it doesnt, as you say, not much lost

Constipation GLP-1s famously slow down digestion, so its no wonder some people start to feel a little stopped up when taking them