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Therapies that rely on scaffold-free cellular approaches, such as ACI, are not designed to handle these mechanical burdens early post-surgery, and thus, utilizing scaffolds with improved bulk mechanical properties could increase efficacy of treatment and promote earlier return to normal activity in these knees

Follow-up testing at 6-8 weeks and 12-16 weeks allows monitoring of metabolic parameters and ensures the peptide is not producing unexpected effects

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures