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Additionally, if you develop symptoms suggestive of gallbladder diseasesuch as right upper abdominal pain, particularly after eating fatty foods, accompanied by nausea or jaundicecontact your GP, as rapid weight loss can increase the risk of gallstones, a warning highlighted in the MHRA safety information for GLP-1 receptor agonists

The key difference: EVOKE+ allowed participants with cerebral small vessel disease

D'Orazio J, Jarrett S, Amaro-Ortiz A, et al

doi:10.1038/sj.ijir.3900582

35 Regional prevalence varies significantly due to ethnic, genetic, and lifestyle factors, with the lowest rates observed in Western Europe and the highest in Latin America, ranging from 25.1% to 44.3%