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492 It acts as a transcriptional co-activator through direct interaction with various proteins, such as the TATA-binding protein, RPB5 subunit of RNA polymerase II, TF IIH, TF IIB, and the proteins of basic domain-leucine zipper (bZIP) family, including the cyclic AMP-response element (CRE)-binding protein (CREB)

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Sexual dysfunction and sex hormone abnormalities in patients with cirrhosis: review of pathogenesis and management