Unlike CD, HT does not have a single universally accepted dietary trigger, which makes the proposed role of gluten more controversial and more clinically difficult to translate ( The association between CD and autoimmune thyroid disease is nevertheless clinically consistent
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10.1016/S0002-9440(10)62498-4 Am
Hence, in certain tumors, abnormal MET activation may diminish the effectiveness of ICIs by increasing PD-L1 expression, whereas in other tumors, MET dysregulation may potentiate the effectiveness of ICIs by reducing PD-L1 expression
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