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Nrf2 pathway is a major target for sulforaphane

Researchers and medical providers still dont fully understand the Herxheimer reaction, but they have a theory

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Kuroiwa-Trzmielina J, de Conti A, Scolastici C, Pereira D, Horst MA, Purgatto E, et al

A significant portion of participants reported ongoing use of preventative migraine medications, which may have influenced their responsiveness to CGRP infusion