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Molecule Complexity Matrix Not every molecule requires the same manufacturing infrastructure

Using fine needles (30-32 gauge) minimizes discomfort and bruising

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Due to its reduced blood supply, the TME can impair the efficacy of radiotherapy as this reduces the accessibility of radio-sensitizers to the area (Koukourakis and Giatromanolaki, 2020

Insert the needle at a 45 to 90 degree angle (90 degrees if you have adequate subcutaneous fat, 45 degrees if you are leaner)