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This has been clearly demonstrated in multiple studies discussed here showing an increased immune activation in ES animals which is reversible by probiotics [80, 81, 87, 91]
Wisniewski, J
10.1111/j.1744-7909.2009.00848.x 137 ZaffagniniM.BedhommeM.MarchandC
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These methyl groups are crucial for various biological processes like DNA methylation, a key mechanism that controls which of our genes are turned on and off
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