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Well-differentiated tumors form large nests and islands with abundant eosinophilic cytoplasm, intercellular bridges, and keratin pearls, whereas high-grade lesions exhibit marked pleomorphism, hyperchromasia, and frequent atypical mitoses with small irregular nests at the invasive front

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When this enzyme is overwhelmed, and too much-oxidized GSSG accumulates (compared to the active GSH), your cells become susceptible to damage

Role of xenobiotics in the induction and progression of fatty liver disease