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If using a prefilled syringe (PFS) for SC administration in FIH studies, it should preferably contain the highest dose, using either additional dose strengths (concentrations or volumes) or down dosing the syringe to administer lower doses (although this approach is not recommended)
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Matching vial supply to cycle length Here's how 100mg aligns with common protocols at standard 2mg dosing: 2mg daily, 5x/week (10mg/week): 100mg = 10 weeks of supply Matches well with 8-12 week cycles One vial covers most standard protocols 2mg daily, 7x/week (14mg/week): 100mg = ~7 weeks of supply May need 1.5-2 vials for 12-week cycle One vial covers shorter 4-6 week cycles with extra 2mg three times weekly (6mg/week): 100mg = ~16 weeks of supply One vial covers even extended cycles May have leftover for maintenance or second cycle The 50mg vial guide provides comparison for smaller vial sizes if 100mg exceeds your needs
& Barres, B
Its a tri-agonist targeting three separate receptor systems simultaneously: The GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors
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