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It is often called the "master antioxidant" because it does more than just neutralize free radicalsunstable molecules that can damage cells

170 This binding increases PDZK1 expression, potentially leading to reduced urate excretion

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Evidence for histogenesis by mllerian metaplasia of coelomic epithelium

With toxicity, manganese-induced damage is found in the substantia nigra, globus pallidus, and caudate nucleus with depletion of dopamine and serotonin levels and has been linked to psychiatric changes followed by impaired motor activity with muscle rigidity and tremors