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In the early twentieth century, neurologist Stern and his team, investigating substance transportation between the brain, cerebrospinal fluid, and peripheral blood, identified a semipermeable barrier separating the brain from the rest of the body, facilitating bidirectional movement, and named it the bloodbrain barrier

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In diet-induced MASLD rodent models, hepatic CAT enzymatic activity showed a non-significant difference as compared to respective standard chow diet-fed animals (Jung and Kim 2013

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