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3.2.7 Other PD-related genes/proteins potentially associated with ferroptosis The absence of CISD1, an iron-rich outer mitochondrial membrane protein, triggers mitochondrial dysfunction alongside the depletion of striatal dopamine and TH, thus facilitating the advancement of PD and the worsening of its clinical manifestations (172)

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Nerve Protection: Recent studies show that patients receiving IV glutathione along with oxaliplatin chemotherapy had a significant reduction in Pins and Needles pain (neuropathy) compared to those who did not receive it