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This variability in outcomes makes determining appropriate patient care very challenging

As a cost-effective and nutrient-dense by-product of beer brewing, it represents an ideal and economical resource for multiple applications [26]

The gut-skin axis is a well-documented connection

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Topical application of GHK-Cu accelerates wound closure (full-thickness excisional wounds in rodents, wound area tracing, digital planimetry), increases granulation tissue thickness (H&E histology), promotes re-epithelialisation (K14/K5 basal keratinocyte IHC, Ki-67 proliferation), and reduces scar width and fibrosis (Massons trichrome, collagen bundle organisation by SHG microscopy)