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AMPK is thought to be a tumor suppressor, too, essentially starving cells while they attempt to form cancerous tumors (though after cancer has developed, AMPK can sometimes promote tumor growth instead).14 As an antimicrobial agent We know that berberine has long been used as an antimicrobial agent in traditional Chinese medicine, and it remains a treatment for diarrhea from both bacterial infections and noninfectious conditions.16 (Ironically, diarrhea and stomach pain are sometimes side effects when you start taking berberine.)

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Pan A, Sun Q, Bernstein AM, Schulze MB, Manson JE, Stampfer MJ, Willett WC, Hu FB

These results suggest the essential contribution of GLP-1R-mediated insulin secretion in the pancreas-liver axis necessary for the subsequent effects of G49

its another to explore the evidence backing these claims