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Published evidence comparing drug costs to outcome measures for health insurers/systems remains sparse, but one study compared the treatment of type 2 diabetes with insulin versus treatment with GLP-1s and found that the higher drug and outpatient costs associated with GLP-1 treatment were offset by a reduction in healthcare costs from emergency visits and inpatient admissions

Increased FDA scrutiny on peptide skincare products making drug claims has also accelerated through 2025 and 2026

Optimal dosing, frequency, and duration are completely unclear

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Abbreviations ART, assisted reproductive technology