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Excess cortisol production from being in a chronic state of stress can lower progesterone production increasing estrogen dominance

For patients with hypothyroidism, increasing antioxidant intake and improving oxidative status may help manage the underactive thyroid condition alongside medical treatment

Funding Statement This work was supported by grants from the National Natural Science Foundation of China (82130034), the Innovation Capability Support Program of Shaanxi (2021TD-57), and the Li Yunqing Expert Workstation of Yunnan Province (202005AF150014)