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2025;48(1 Suppl 1):S181-S206

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(37) demonstrated that silencing NTSCalcr neurons in mice resulted in chronic increases in food intake and subsequent weight gain (37)

Unlike injectable versions, oral medications do not require refrigeration, making them easier to store, transport, and ship particularly for patients who travel frequently

For instance, genetic ablation of GPX4 promotes the accumulation of oxidized cardiolipin within mitochondriaa [54], and lipid peroxidation has been reported to emerge initially in mitochondrial membranes before propagating to other cellular compartments