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The ABR genes and class categories were also confirmed by ResFinder 41 , Antibiotic Resistance Gene-ANNOTation (ARG-ANNOT) 42 and Comprehensive Antibiotic Resistance Database (CARD) 17
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Under iron-rich conditions, F-box and leucine-rich repeat protein 5 (FBXL5) mediates the ubiquitination and degradation of IRP2, leading to suppression of TfR1, increased iron storage in ferritin and increased export via FPN
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