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Additionally, GIP receptor expression in hypothalamic regions and oligodendrocytes suggests central nervous system actions that may synergize with GLP-1 to reduce appetite and food intake while potentially mitigating GLP-1-associated nausea, thereby improving treatment tolerability [36,41,42]

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The combination of 968 and PD-L1 has been shown to enhance the bodys immune response to ovarian cancer, and the combination of 968 with the autophagy inhibitor chloroquine (CQ) has been demonstrated to have a synergistic effect on the growth of NSCLC cells [149, 150]