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Antioxidant and Antitumor Effects Based on epithalamin research, epithalon is believed to have antioxidant activity that contributes to the regulation of cytokines and C-reactive protein, leading to research interest in its use as a treatment of a number of inflammatory ailments like arthritis and ulcerative colitis [11, 12]

Monolayers of hiPSC-derived endothelial cells from Alzheimer's patients with PSEN1 and PSEN2 mutations, differentiated with a chemically defined medium, possessed a low TEER, reduced expression of claudin-5, occludin, and ZO1 protein, and impaired glucose transport (Raut et al., 2021)

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Conclusion While we have a good understanding of the consequences of micronutrient deficiencies on cognition, we know considerably less about the cognitive effects of micronutrient supplementation