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SGLT-is significantly reduce the risk of HF by 3040% in individuals with T2D with established or high risk of CVD according to previous large-scale RCTs, and the HF benefits exists no matter the ejection fraction is preserved or reduced

53.5% with T2D), silymarin 700 mg three times daily for 48 weeks did not reduce the primary efficacy outcome, i.e., a decrease of 30% or more in NAS compared to placebo (32.7% vs 26.0%, p = 0.467) [66]

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Many facilities offer package pricing for multiple treatments and maintenance protocols that improve overall cost-effectiveness compared to individual session pricing