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[PubMed] Houamed KM, Kuijper JL, Gilbert TL, Haldeman BA, OHara PJ, Mulvihill ER, Almers W, Hagen FS

GGT (Gamma-Glutamyl Transferase) What it measures: A liver enzyme involved in glutathione metabolism

Citrulline produced a significantly higher and more sustained increase in plasma arginine roughly double the area under the curve compared to arginine supplementation

These markers don't predict exact GLP-1 response, but they illuminate whether your genetic baseline favors robust natural production or may benefit from additional support

Your risk for early worsening increases if you have high baseline A1C, long-standing diabetes, or existing diabetic macular edema