After four weeks, the dose can be increased to 7 mg or 14 mg, based on individual response and tolerability Wegovy (Injectable): The initial dose of Wegovy is generally 0.25 mg injected once weekly for four weeks
External resources American Journal of Clinical Nutrition: Nutritional priorities to support GLP-1 therapy for obesity Endocrine Society: Protein may protect against muscle loss on semaglutide (ENDO 2025) Impact of semaglutide on body composition in adults with overweight or obesity: STEP 1 study For researchers serious about optimizing their peptide protocols and nutrition strategies during GLP-1 therapy, SeekPeptides offers the most comprehensive resource available, with evidence-based guides, proven protocols, personalized calculators, and a community of thousands who have navigated these exact questions
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Moreover, oral GLP-1 RA are also under development and will provide an alternative option
