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Gastrointestinal adverse effects, including nausea and vomiting, remain the most commonly reported side effects and may influence adherence during treatment initiation

Participants in these trials experienced notable improvements in glycemic control, making tirzepatide particularly beneficial for those managing diabetes alongside obesity

May cause a slight increase in the risk of ketoacidosis in some patients

Bottom-up methodologies encompass chemical vapor deposition, microemulsion synthesis, hydrothermal synthesis, green chemistry techniques, inert gas condensation, precipitation, microwave-assisted synthesis, ultrasonic-assisted synthesis, and biotemplated synthesis

Not appropriate with uncontrolled high blood pressure or cardiovascular disease