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Not everyone experiences this side effect, but some people do report a mild to moderate burning or stinging sensation or discomfort after their injection, he says

They work by mimicking the bodys natural GLP-1 hormone, which regulates blood sugar, slows stomach emptying, suppresses appetite, and alters gut motility

Long-Term Maintenance Over time, if your body can maintain healthy B12 levels through diet or other absorption methods, injections may taper off

"And also not having all of your nutrient needs met as well." She explained that often, people will say that they just aren't hungry enough to eat what they need to eat

When Retatrutides GLP-1, GIP, and glucagon effects stop simultaneously, the metabolic rebound may be more pronounced