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The primary goal of uterine infertility therapies is to promote endometrial regeneration (Zou et al., 2025)

Consistent with the potency gained from introducing the 6-carboxylic acid motif in the benzimidazole region, the cryo-EM structure showed that the carboxylic acid of PF-06883365 is making a productive interaction with an arginine residue at position 380 in the GLP-1R binding pocket

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found that women with unexplained infertility had significantly lower kisspeptin levels compared to women whose infertility was attributable to male-factor causes

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