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10.1517/17460441.2013.741580 76 PattersonJ

Notably, in models of type 2 diabetes, PCs confer neuroprotection by modulating NF-E2/STAT1 signaling, attenuating Janus kinase activity, and inhibiting cell apoptosis, thereby reducing cerebrovascular lesions and associated neurological deficits (Wu et al., 2015

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7 Discussion Currently, the main application of GLP-1RA is still in the field of diabetes, especially for type 2 diabetes patients, GLP-1RA provides an effective means of blood sugar control and may provide additional cardiovascular, kidney and other system benefits