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Narcan effects are temporary, and the overdose state can return in 30-90 minutes.

doi:10.1073/pnas.0709747104

Yet, when someone with B12 deficiency reports that symptoms re-occur 4-5 weeks after a B12 injection, and wants to inject more often, all of a sudden, this person is mislabelled as suffering from the placebo effect of B12 injections

The timeline for availability: Lilly will likely price retatrutide at or above Zepbound levels, given the superior efficacy data

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